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1-Octanol

1-辛醇
Company: EMD Millipore
Catalog#: 820931
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In situ Chemotaxis Assay in Caenorhabditis elegans (for the Study of Circadian Rhythms)
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2014-02-05
[Abstract]  Olfaction is a well-studied sensory mechanism in Caenorhabditis elegans (C. elegans). The nematodes respond to a wide range of chemicals by either attraction, repulsion or a mixture thereof (Bargmann et al., 1993). We have used olfaction to characterize behavioural and molecular circadian rhythms in C. elegans. The circadian clock is a biological oscillator that provides an endogenous temporal structure that approximately matches the 24-hour periodicity in the environment (due to the rotational movement of the Earth). Circadian rhythms are present in most organisms from cyanobacteria to humans and they typically regulate sensory functions among many other processes. Olfaction is under circadian control in many animals (Granados-Fuentes et al., ... [摘要]  嗅觉是Caenorhabditis elegans中的一个充分研究的感觉机制（ C. elegans ）。线虫通过吸引，排斥或其混合物对大范围的化学物质响应（Bargmann等人，1993）。我们使用嗅觉来表征行为和分子昼夜节律。 elegans 。生物钟是生物振荡器，其提供近似匹配环境中的24小时周期性（由于地球的旋转运动）的内生时间结构。昼夜节律存在于从蓝细菌到人的大多数生物体中，并且它们通常在许多其他过程中调节感觉功能。在许多动物中嗅觉处于昼夜节律控制之下（Granados-Fuentes等人，2006; Granados-Fuentes等人，2011; Tanoue等人， 2008; Krishnan等人，1999）。该协议被设计为允许在短时间间隔内，在蠕虫生长的同一板中（以避免可能干扰节律的洗涤步骤）以及在食物存在下，评估一群蠕虫的嗅觉。

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