| Isolation of Flavonoids from Piper delineatum Leaves by Chromatographic Techniques
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Author:
Date:
2016-07-20
[Abstract] The genus Piper (Piperaceae) is widely distributed in the tropical and subtropical regions of the world, and species belonging to this genus are included in the Ayurvedic system of medicine and in folklore medicine of Latin America. Phytochemical investigations of Piper species have led to the isolation of several classes of physiologically active compounds such as alkaloids, amides, pyrones, dihydrochalcones, flavonoids, phenylpropanoids, lignans and neolignans. In an ongoing investigation of bioactive secondary metabolites from Piper species, herein, we describe the isolation procedure of nine flavonoids, including two chalcones and two flavanones from the leaves of Piper delineatum Trel. (Piperaceae), a shrub native to tropical regions of the ...
[摘要] 蓟属（Piperaceae）广泛分布在世界的热带和亚热带地区，属于该属的种属包括在医学的阿育吠陀系统和拉丁美洲的民间传说医学中。 对Piper物质的植物化学研究已导致分离几类生理活性化合物，例如生物碱，酰胺，吡喃酮，二氢查耳酮，类黄酮，苯丙素类，木酚素和新木脂体。 在对来自Piper种的生物活性次级代谢物的进行中的研究中，我们描述了九种类黄酮的分离程序，包括来自叶脉的两种查耳酮和两种黄烷酮 。 （Pi科），灌木本地对美洲的热带地区。 所有化合物通过光谱和光谱测定法进行阐明，并与文献中报道的数据进行比较。
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| Isolation and Characterization Procedure for Indole Alkaloids from the Marquesan Plant Rauvolfia Nukuhivensis
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Author:
Date:
2015-10-20
[Abstract] A plethora of natural products, mostly secondary metabolites, are isolated and purified from many different organisms, like plants, fungi, algae, marine invertebrates, etc. The extraction procedure is specific to each organism, but some guidelines are usually followed for any purification procedure regarding targeted metabolites, such as alkaloids. Alkaloids are secondary metabolites that contain basic nitrogen in their structures and they are often associated with interesting biological properties especially in pharmacology field. This protocol describes the isolation procedure of indole alkaloids from Rauvolfia nukuhivensis directly from the ethanol extract of the plant material yielding different skeleton-type compounds including non-basic derivatives (ajmaline, ...
[摘要] 从许多不同的生物体如植物，真菌，藻类，海洋无脊椎动物等分离和纯化了大量天然产物，主要是次级代谢物。提取程序对每个生物体是特异性的，但是关于靶向代谢物（例如生物碱）的任何纯化程序通常遵循一些指导。生物碱是在其结构中含有碱性氮的次级代谢物，并且它们通常与有趣的生物学性质相关，特别是在药理学领域。该方案描述了直接从植物材料的乙醇提取物中的来自真鞭毛虫的吲哚生物碱的分离过程，产生不同的骨架类化合物，包括非碱性衍生物（水杨酸，胭脂碱，大线和β-咔啉）。该程序详述了使用光谱技术（NMR，MS，UV）从植物收集到分子水平表征新的或已知的分离的化合物的指南和步骤。我们详细描述了化合物纯化之后的萃取和分馏方法，以及它们的物理化学表征。该程序通过从大白菜Rauvolfia nukuhivensis的树皮中纯化大量吲哚生物碱的实例来说明。
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