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Copper Gauze

铜纱

Company: Thermo Fisher Scientific
Catalog#: AA42777HZ
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Social Recognition Memory Test in Rodents
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2016-05-05
[Abstract]  Social recognition memory is essential for the establishment and maintenance of a rodent colony. Recognition memory is important for social hierarchy, mate and offspring recognition, and interspecies recognition. Interspecies recognition is vital for recognizing frequent visitors to the animal’s habitat and whether or not the visitors pose a threat to the animals or colony (Macbeth et al., 2009; Noack et al., 2010). Here, we describe a protocol which effectively and reproducibly measures the social recognition for a juvenile male, a female, a mouse of another strain, and a rat. This task relies on the animal’s innate tendency to explore a novel social partner and decrease the exploration of a known familiar social partner (Thor et al., 1982). A significant ... [摘要]  社会识别记忆对于建立和维持啮齿动物群落是必不可少的。识别记忆对于社会等级,伴侣和后代识别以及种间识别是重要的。种间识别对于识别经常访问动物栖息地的游客以及游客是否对动物或殖民地构成威胁是至关重要的(Macbeth等人,2009; Noack等人, em,2010)。在这里,我们描述一个协议,有效和可重复地测量的少年男性,女性,另一种应变和老鼠的小鼠的社会认可。这个任务依赖于动物的先天倾向来探索一个新的社会伙伴,并减少对已知熟悉的社会伙伴的探索(Thor等人,1982)。合作伙伴从训练阶段到召回阶段的探索显着减少表明了社会伙伴的记忆。此外,我们描述了社会认识程序,习惯性的习惯范例,其密切模仿在殖民地中的动物之间的典型的短的,频繁的相互作用(Dantzer等人,1987; Winslow和Camacho,1995)。此外,嗅觉是社会认知的关键组成部分,以测试嗅觉,参见Jacobs等人(2016)。在这个协议,我们使用转基因NR2A过表达小鼠表明如何可能出现社会认知记忆的损害。

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