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Recombinant Murine IL-5

重组鼠IL-5

Company: PeproTech
Catalog#: 215-15
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Bone Marrow Derived Eosinophil Cultures
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2014-06-20
[Abstract]  Eosinophils are multifunctional effector cells implicated in the pathogenesis of a variety of diseases including asthma, eosinophil gastrointestinal disorders and helminth infection. Mouse bone marrow derived progenitor cells can be differentiated into eosinophils following IL-5 exposure. These bone marrow derived eosinophils are fully differentiated at the end of a 14 day culture based on morphology and expression of molecular markers.
[摘要]  嗜酸性粒细胞是涉及多种疾病的发病机理的多功能效应细胞,包括哮喘,嗜酸性粒细胞胃肠道疾病和蠕虫感染。 小鼠骨髓来源的祖细胞可以在IL-5暴露后分化成嗜酸性粒细胞。 这些骨髓衍生的嗜酸性粒细胞在14天培养结束时基于分子标志物的形态学和表达完全分化。

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