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Author:
Date:
2020-09-20
[Abstract] Songbirds, such as the zebra finch, are a popular animal model for studying the neural basis of vocal and complex skill learning. Adult male zebra finches produce courtship song toward females (referred to as ‘directed song’) and recording and analyzing sounds of directed song along with underlying neural activity is important for investigating behavioral and neural mechanisms of song production and learning. However, recording of directed song is easily contaminated by calls that are often as loud as directed songs and frequently produced by a female bird is presented in the same sound-recording chamber to elicit directed song. We developed a new surgical procedure to relatively easily and almost completely devocalize female zebra finches semi-permanently, without affecting other ...
[摘要] [摘要 ] 鸣禽（例如斑马雀科）是一种流行的动物模型，用于研究声音和复杂技能学习的神经基础。成年男性斑马雀对女性产生求爱歌曲（被称为“定向歌曲”），记录和分析定向歌曲的声音以及潜在的神经活动对于调查歌曲产生和学习的行为和神经机制很重要。然而，定向歌曲的记录容易被通常与定向歌曲一样响亮并且通常由雌鸟产生的呼叫污染在同一录音室中以引起定向歌曲。我们开发了一个新的 外科手术程序可以相对轻松地，几乎完全消除半永久性地消除雌性斑马雀，而不会影响其他行为。此程序使研究人员可以录制定向歌曲，几乎不会受到女性呼叫的污染。该程序也可以用来消除雄鸟的声音，因此，对于各种实验目的，例如长期消除雄鸟唱歌过程中的听觉反馈，具有很大的潜力。
[背景 ] 正如人类婴儿学习与成人产生复杂的语音声音，年轻的鸣禽学习产生复杂发声（即在发展的关键时期，从成年导师，歌曲）。由于生命科学研究中的普通动物模型（例如小鼠和猴子）不表现出声音学习，因此鸣禽为研究声音学习的神经基础（人类语言获取的重要要素）提供了绝佳的机会（Doupe和Kuhl，1999； Bolhuis 等）等人，2010）。此外，鸟类的鸣叫学习严重依赖于神经节- 丘脑- ...
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