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Heparin−Agarose

肝素 - 琼脂糖

Company: Sigma-Aldrich
Catalog#: H6508
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Native BAD-1 Binding to Heparin-agarose
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Date:
2014-04-05
[Abstract]  BAD-1 is an adhesin created by the dimorphic fungus Blastomyces dermatitidis, the causative agent of blastomycosis. We have determined that it has an affinity for heparin, which may explain its impact on virulence and human immune function as a number of cells related to immune function have heparin like moieties on their surfaces. This assay allows a quantification of binding between soluble BAD-1 and immobilized heparin. [摘要]  BAD-1是由两种类型的真菌Blastomyces dermatitidis(芽生菌病的病原体)产生的粘附素。 我们已经确定它对肝素具有亲和力,这可以解释其对毒力和人类免疫功能的影响,因为许多与免疫功能相关的细胞在其表面上具有肝素样部分。 该测定允许定量可溶性BAD-1和固定化肝素之间的结合。

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