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Author:
Date:
2015-12-20
[Abstract] Accurate live tumor imaging in mice is now possible by means of high-resolution positron emission tomography (micro-PET) and X-ray computed tomography (micro-CT). By providing a powerful tool to examine biological samples with complex structure in vivo, this technology generated a significant advance in the cancer research field, particularly regarding the ability to perform longitudinal studies in combination with a therapeutic intervention. Here, we describe methods to optimize visualization of murine lung tumors by micro-PET, micro-CT and combined micro-PET-CT.
[摘要] 通过高分辨率正电子发射断层扫描（micro-PET）和X射线计算机断层扫描（micro-CT），现在可以在小鼠中精确的活肿瘤成像。 通过提供用于在体内检查具有复杂结构的生物样品的强大工具，该技术在癌症研究领域中产生了显着的进步，特别是关于结合治疗干预进行纵向研究的能力。 在这里，我们描述的方法，通过微型PET，微CT和组合的微PET-CT优化鼠肺肿瘤的可视化。
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