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Heated workstation with gas evacuation system and a face mask for induction and maintenance of anesthesia

带有排气系统的加热工作站和用于感应和维持麻醉的面罩

Company: Baxter
Catalog#: AS-01-0491
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Rat Model of Chronic Midthoracic Lateral Hemisection
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Date:
2013-09-20
[Abstract]  Although most spinal cord injuries (SCI) are anatomically incomplete, only limited functional recovery has been observed in people and rats with partial lesions. To address why surviving fibers cannot mediate more complete recovery, it is important to evaluate the physiological and anatomical status of spared fibers. These experiments require use of animal models. Here we describe a midthoracic unilateral spinal cord hemisection (HX; corresponds to Brown-Sequard lesion in humans) in adult rats. This is a useful animal model for partial injuries because there is a clear lesion of one entire side of the cord with intact fibers remaining on the contralateral side. This model allows the study and comparison of how acute and chronic trauma affect function of the surviving fibers. [摘要]  虽然大多数脊髓损伤(SCI)在解剖学上是不完全的,但是在具有部分损伤的人和大鼠中仅观察到有限的功能恢复。 为了解决为什么存活的纤维不能介导更完全的恢复,重要的是评估备用纤维的生理和解剖状态。 这些实验需要使用动物模型。 在这里我们描述成人大鼠的midthoracic单侧脊髓半切(HX;对应于人类中的棕色Sequard病变)。 这是用于部分损伤的有用的动物模型,因为在完整纤维保留在对侧的情况下,存在帘线的整个侧面的清楚的病变。 该模型允许研究和比较急性和慢性创伤如何影响存活纤维的功能。

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