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Author:
Date:
2015-05-05
[Abstract] After stroke and brain contusion, serum proteins extravasate into nerve tissue through disrupted blood-brain barrier (BBB). Because extravasations of serum proteins result in vasogenic brain edema, serum albumin level in the brain is an indicator of BBB disruption and brain edema after brain insults. In this protocol, extravasation of endogenous albumin is measured in the damaged mouse brain, which would be valuable in the evaluation of vasogenic brain edema formation (Michinaga et al., 2014).
[摘要] 在中风和脑挫伤后，血清蛋白通过破裂的血脑屏障（BBB）外渗到神经组织中。 因为血清蛋白的外渗导致血管性脑水肿，脑中的血清白蛋白水平是脑损伤后BBB破坏和脑水肿的指标。 在该方案中，在损伤的小鼠脑中测量内源性白蛋白的外渗，这在评价血管性脑水肿形成中是有价值的（Michinaga等人，2014）。
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