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Histone

组蛋白

Company: Roche Diagnostics
Catalog#: 10223565001
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Quantitative Enzyme-linked Immunosorbent Assay (ELISA) to Measure Serum Levels of Murine Anti-histone Antibodies
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Date:
2012-06-20
[Abstract]  Autoimmune disease is characterized with the break of tolerance against self antigens. Anti-histone antibodies can be found in the majority of patients with system lupus erythematosus (SLE) and a number of lupus-prone mouse strains. This protocol describes a reliable method to determine the relative serum titers of anti-histone antibodies in these mice. [摘要]  自身免疫性疾病的特征在于对自身抗原的耐受性的中断。 抗组蛋白抗体可以在系统性红斑狼疮(SLE)和许多易患狼疮的小鼠品系的大多数患者中发现。 该方案描述了确定这些小鼠中抗组蛋白抗体的相对血清滴度的可靠方法。

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