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PE Rat Anti-Mouse CD11b Clone M1/70

PE大鼠抗小鼠CD11b克隆M1 / 70

Company: BD
Catalog#: 557397
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Isolation of CNS-infiltrating and Resident Microglial Cells
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2015-01-20
[Abstract]  Variety of immunological and biochemical studies associated with infection or inflammation in the central nervous system (CNS) utilize CNS-resident and/or infiltrating cells which were isolated from the CNS of naïve and affected mice in order to investigate the underlying mechanisms and the potential roles of the cell populations. Mechanical and enzyme-based single cell preparations of CNS cells are subjected to a density gradient to obtain functional single cells. In combination with cell-specific biomarkers, the function and/or status of resident microglia and infiltrating lymphocytes, including B and T cells as well as macrophages, can be characterized. [摘要]  与中枢神经系统(CNS)中的感染或炎症相关的免疫学和生物化学研究的多样性利用从初始和受影响的小鼠的CNS中分离的CNS驻留和/或浸润细胞,以研究潜在的机制和潜在的作用 的细胞群体。 将CNS细胞的机械和基于酶的单细胞制剂进行密度梯度以获得功能性单细胞。 与细胞特异性生物标志物组合,可以表征驻留小胶质细胞和浸润淋巴细胞(包括B和T细胞以及巨噬细胞)的功能和/或状态。

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