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VECTASHIELD HardSetTM Mounting Medium

VECTASHIELD HardSet TM安装介质

Company: VWR
Catalog#: 01098-050
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In vitro T Cell–DC and T Cell–T Cell Clustering Assays
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2013-10-20
[Abstract]  To get activated, T cells need to find their cognate antigen at the surface of an antigen-presenting cell (APC). Recognition of cognate antigen in the context of the MHC (Major histocompatibility complex) by the TCR (T-Cell Receptor) results in long lasting interactions between T cells and APCs. Subsequently, T cells form homotypic interactions with each other, which is seen as a hallmark of T cell activation. This protocol describes a method to analyze T-APC and T-T conjugation. [摘要]  为了激活,T细胞需要在抗原呈递细胞(APC)的表面找到它们的同源抗原。 通过TCR(T细胞受体)在MHC(主要组织相容性复合物)的上下文中的同源抗原的识别导致T细胞和APC之间的持久的相互作用。 随后,T细胞彼此形成同型相互作用,这被看作是T细胞活化的标志。 该协议描述了一种分析T-APC和T-T共轭的方法。

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