JC-1 Dye (Mitochondrial Membrane Potential Probe)
Company: Thermo Fisher Scientific
Catalog#: T3168
Product evaluation:
Mouse Liver Mitochondria Isolation, Size Fractionation, and Real-time MOMP Measurement
Author:
Date:
2016-08-05
[Abstract]  The mitochondrial pathway of apoptosis involves a complex interplay between dozens of proteins and lipids, and is also dependent on the shape and size of mitochondria. The use of cellular models in past studies has not been ideal for investigating how the complex multi-factor interplay regulates the molecular mechanisms of mitochondrial outer membrane permeabilization (MOMP). Isolated systems have proven to be a paradigm to deconstruct MOMP into individual steps and to study the behavior of ...

Arabidopsis thaliana Embryo Sac Mitochondrial Membrane Potential Stain
Author:
Date:
2014-05-20
[Abstract]  The aim of this experiment is to study mitochondrial functional status in Arabidopsis embryo sacs using the membrane potential indicator JC-1. Changes in the membrane potential are presumed to be due to the opening of the mitochondrial permeability transition pore (MPTP), allowing passage of ions and small molecules. The resulting equilibrium of ions leads in turn to the decoupling of the respiratory chain and the release of cytochrome c into the cytosol, a distinctive feature of the ...

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