Company: Sigma-Aldrich
Catalog#: H6508
Product evaluation:
Native BAD-1 Binding to Heparin-agarose
[Abstract]  BAD-1 is an adhesin created by the dimorphic fungus Blastomyces dermatitidis, the causative agent of blastomycosis. We have determined that it has an affinity for heparin, which may explain its impact on virulence and human immune function as a number of cells related to immune function have heparin like moieties on their surfaces. This assay allows a quantification of binding between soluble BAD-1 and immobilized heparin.

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