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Author:
Date:
2016-03-05
[Abstract] Episodic memory has been defined in humans as the conscious recollection of unique personal past experiences often occurring singly during daily life, including remembrance of what happened, where and when it happened (Tulving, 1972). Here, we propose and describe in details a novel protocol we recently used to test the ability of rats to form and recollect episodic-like memory of previously encountered occasional episodes (Veyrac et al., 2015). During these episodes, the animals are briefly exposed to sets of specific odor–drink associations (what happened) encountered in specific locations (where it happened) within different multisensory enriched environments (in which context/occasion it happened). Memory of the episodes can be tested at relatively short (24 h) or much longer ...
[摘要] 在人类中已经定义了特殊记忆，因为对日常生活中经常发生的独特个人过去经历的自觉记忆，包括记忆发生的事情，发生的时间和地点（Tulving，1972）。在这里，我们提出并详细描述了一种我们最近用来测试大鼠形成和记忆以前遇到的偶发事件的情景样记忆的能力的新方案（Veyrac等，2015）。在这些情节中，动物短暂地暴露于不同的多感官富集环境（在其中发生的情况/场合）中遇到的特定气味饮料组合（发生了什么事）。可以在低或高干扰检索情况下相对较短（24小时）或更长时间（24天）延迟测试剧集的记忆。这种新颖的范例为召回性能的个人记忆特征提供了可能与脑功能网络的不同方面相关的证据。更一般来说，它提供了新的可能性来探索细胞和网络机制，这些机制是脑病变过去事件和记忆功能障碍的记忆。
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