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Dextran sulfate sodium salt

葡聚糖硫酸钠盐

Company: Sigma-Aldrich
Catalog#: 67578
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Single-cell Visualization of Chromosome Transcriptional Territories by RNA-paint
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2016-09-05
[Abstract]  We developed a FISH-based method to directly assess chromosome-wide transcriptional activity, thereby enabling the visualization of the actively transcribed fraction of a chromosome at the single-cell level. We applied this method to probe the activity of X-chromosomes and its instability in the context of human embryonic stem cells and cancer cells. [摘要]  我们开发了基于FISH的方法,以直接评估染色体宽转录活性,从而使单细胞水平的染色体的积极转录部分的可视化。 我们应用这种方法探测X染色体的活动及其在人类胚胎干细胞和癌细胞的上下文中的不稳定性。

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